GMIP Antibody, Biotin conjugated

Code CSB-PA878952LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) GMIP Polyclonal antibody
Uniprot No.
Target Names
GMIP
Alternative Names
ARHGAP46 antibody; GEM interacting protein antibody; GEM-interacting protein antibody; GMIP antibody; GMIP_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human GEM-interacting protein (719-858AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Stimulates, in vitro and in vivo, the GTPase activity of RhoA.
Gene References into Functions
  1. These findings demonstrate a new role of Gem/Gmip/RhoA signaling in cortical actin regulation during early mitotic stages PMID: 25173885
  2. during exocytosis, actin depolymerization commences near the secretory organelle, not the plasma membrane, and secretory granules use a JFC1- and GMIP-dependent molecular mechanism to traverse cortical actin. PMID: 22438581
  3. signalling pathways controlled by two proteins of the Ras superfamily, RhoA and Gem, are linked via the action of the RhoGAP protein Gmip PMID: 12093360
  4. Variations in the GMIP gene can confer susceptibility to major depressive disorder. PMID: 16086184
Database Links

HGNC: 24852

OMIM: 609694

KEGG: hsa:51291

STRING: 9606.ENSP00000203556

UniGene: Hs.49427

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