GMIP Antibody, Biotin conjugated

Code CSB-PA878952LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) GMIP Polyclonal antibody
Uniprot No.
Target Names
GMIP
Alternative Names
ARHGAP46 antibody; GEM interacting protein antibody; GEM-interacting protein antibody; GMIP antibody; GMIP_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human GEM-interacting protein (719-858AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Stimulates, in vitro and in vivo, the GTPase activity of RhoA.
Gene References into Functions
  1. These findings demonstrate a new role of Gem/Gmip/RhoA signaling in cortical actin regulation during early mitotic stages PMID: 25173885
  2. during exocytosis, actin depolymerization commences near the secretory organelle, not the plasma membrane, and secretory granules use a JFC1- and GMIP-dependent molecular mechanism to traverse cortical actin. PMID: 22438581
  3. signalling pathways controlled by two proteins of the Ras superfamily, RhoA and Gem, are linked via the action of the RhoGAP protein Gmip PMID: 12093360
  4. Variations in the GMIP gene can confer susceptibility to major depressive disorder. PMID: 16086184
Database Links

HGNC: 24852

OMIM: 609694

KEGG: hsa:51291

STRING: 9606.ENSP00000203556

UniGene: Hs.49427

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